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Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation.
1. The interaction of cyclosporin A (CyA) with p-glycoprotein during intestinal uptake was investigated by a combination of in vitro experiments with human Caco-2 cells and an intubation study in healthy volunteers. 2. CyA uptake into the cells was not saturable and exhibited only a low temperature...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
1996
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1909843/ https://ncbi.nlm.nih.gov/pubmed/8842452 |
| टैग : |
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