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The mutation rate of the human mtDNA deletion mtDNA4977.
The human mitochondrial mutation mtDNA4977 is a 4,977-bp deletion that originates between two 13-bp direct repeats. We grew 220 colonies of cells, each from a single human cell. For each colony, we counted the number of cells and amplified the DNA by PCR to test for the presence of a deletion. To es...
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| Autori principali: | , , , , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914802/ https://ncbi.nlm.nih.gov/pubmed/8808591 |
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