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Heat shock transcription of the groESL operon of Agrobacterium tumefaciens may involve a hairpin-loop structure.

The groESL operon of Agrobacterium tumefaciens was cloned and sequenced and found to be highly homologous to previously analyzed groE operons in nucleotides of the coding region and in amino acid sequence. Transcription of this operon in A. tumefaciens was considerably stimulated by heat shock. Prim...

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Main Authors: Segal, G, Ron, E Z
格式: Artigo
語言:en
出版: 1993
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC204629/
https://ncbi.nlm.nih.gov/pubmed/8098329
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spelling pubmed-2046292003-12-01 Heat shock transcription of the groESL operon of Agrobacterium tumefaciens may involve a hairpin-loop structure. Segal, G Ron, E Z J Bacteriol Research Article The groESL operon of Agrobacterium tumefaciens was cloned and sequenced and found to be highly homologous to previously analyzed groE operons in nucleotides of the coding region and in amino acid sequence. Transcription of this operon in A. tumefaciens was considerably stimulated by heat shock. Primer extension analysis revealed that the groE transcripts from cells under heat shock were initiated from the same promoter (a sigma-70-like promoter) as transcripts from untreated cells, and no sequence homology with the Escherichia coli heat shock promoters was observed. The DNA sequence downstream of the transcription start site contains an inverted repeat that has a strong similarity to other groESL operons of both gram-positive and gram-negative bacteria (such as cyanobacteria and chlamydiae). This conserved region is thought to form a hairpin-loop structure and may play a role in gene regulation during heat shock. 1993-05 /pmc/articles/PMC204629/ /pubmed/8098329 Text en
institution US National Library of Medicine
collection PubMed Central
language en
format Article
topic Research Article
spellingShingle Research Article
Segal, G
Ron, E Z
Heat shock transcription of the groESL operon of Agrobacterium tumefaciens may involve a hairpin-loop structure.
description The groESL operon of Agrobacterium tumefaciens was cloned and sequenced and found to be highly homologous to previously analyzed groE operons in nucleotides of the coding region and in amino acid sequence. Transcription of this operon in A. tumefaciens was considerably stimulated by heat shock. Primer extension analysis revealed that the groE transcripts from cells under heat shock were initiated from the same promoter (a sigma-70-like promoter) as transcripts from untreated cells, and no sequence homology with the Escherichia coli heat shock promoters was observed. The DNA sequence downstream of the transcription start site contains an inverted repeat that has a strong similarity to other groESL operons of both gram-positive and gram-negative bacteria (such as cyanobacteria and chlamydiae). This conserved region is thought to form a hairpin-loop structure and may play a role in gene regulation during heat shock.
author Segal, G
Ron, E Z
author_facet Segal, G
Ron, E Z
author_sort Segal, G
title Heat shock transcription of the groESL operon of Agrobacterium tumefaciens may involve a hairpin-loop structure.
title_short Heat shock transcription of the groESL operon of Agrobacterium tumefaciens may involve a hairpin-loop structure.
title_full Heat shock transcription of the groESL operon of Agrobacterium tumefaciens may involve a hairpin-loop structure.
title_fullStr Heat shock transcription of the groESL operon of Agrobacterium tumefaciens may involve a hairpin-loop structure.
title_full_unstemmed Heat shock transcription of the groESL operon of Agrobacterium tumefaciens may involve a hairpin-loop structure.
title_sort heat shock transcription of the groesl operon of agrobacterium tumefaciens may involve a hairpin-loop structure.
publishDate 1993
url https://ncbi.nlm.nih.gov/pmc/articles/PMC204629/
https://ncbi.nlm.nih.gov/pubmed/8098329
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