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The budding yeast PP2A(Cdc55) protein phosphatase prevents the onset of anaphase in response to morphogenetic defects

Faithful chromosome transmission requires establishment of sister chromatid cohesion during S phase, followed by its removal at anaphase onset. Sister chromatids are tethered together by cohesin, which is displaced from chromosomes through cleavage of its Mcd1 subunit by the separase protease. Separ...

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Autors principals: Chiroli, Elena, Rossio, Valentina, Lucchini, Giovanna, Piatti, Simonetta
Format: Article
Idioma:English
Publicat: The Rockefeller University Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064206/
https://ncbi.nlm.nih.gov/pubmed/17502422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200609088
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