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Prognostic significance of p53 overexpression and mutation in colorectal adenocarcinomas.

The p53 tumour-suppressor gene is found altered in the majority of colorectal cancers. Lesions include allelic loss, mutation of the gene and overexpression of the p53 protein. All of these lesions have been analysed for prognostic significance, and whereas both mutation and allelic loss have been s...

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Bibliografiske detaljer
Main Authors: Smith, D. R., Ji, C. Y., Goh, H. S.
Format: Artigo
Sprog:English
Udgivet: Nature Publishing Group 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074579/
https://ncbi.nlm.nih.gov/pubmed/8688324
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