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Design of polydactyl zinc-finger proteins for unique addressing within complex genomes

Zinc-finger proteins of the Cys(2)-His(2) type represent a class of malleable DNA-binding proteins that may be selected to bind diverse sequences. Typically, zinc-finger proteins containing three zinc-finger domains, like the murine transcription factor Zif268 and the human transcription factor Sp1,...

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Autori principali: Liu, Qiang, Segal, David J., Ghiara, Jayant B., Barbas, Carlos F.
Natura: Articolo
Lingua:en
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20811/
https://ncbi.nlm.nih.gov/pubmed/9159105
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