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Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

Intraperitoneal injection of purified recombinant Acrp30 lowers glucose levels in mice. To gain insight into the mechanism(s) of this hypoglycemic effect, purified recombinant Acrp30 was infused in conscious mice during a pancreatic euglycemic clamp. In the presence of physiological hyperinsulinemia...

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Autori principali: Combs, Terry P., Berg, Anders H., Obici, Silvana, Scherer, Philipp E., Rossetti, Luciano
Natura: Articolo
Lingua:en
Pubblicazione: American Society for Clinical Investigation 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC209474/
https://ncbi.nlm.nih.gov/pubmed/11748271
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