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Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase

Secretory granules of human dermal mast cells contain a chymotrypsin- like serine proteinase called chymase. In this study, we demonstrate that the inactive cytokine, 31 kD interleukin 1 beta (IL-1 beta), can be converted rapidly to an 18 kD biologically active species by human mast cell chymase. Th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Formatua: Artikulua
Hizkuntza:English
Argitaratua: The Rockefeller University Press 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118970/
https://ncbi.nlm.nih.gov/pubmed/1919436
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