CLASSIFICATION OF THYMUS-DERIVED AND MARROW-DERIVED LYMPHOCYTES BY DEMONSTRATION OF THEIR ANTIGEN-BINDING CHARACTERISTICS

Antigen-binding cells of T and B origin can readily be determined by quantitating the number of sheep erythrocytes per rosette after glutaraldehyde fixation. The T(1) and T(2) populations have low antigen-binding properties and are very unstable without fixation. The B(1) and B(2) populations are st...

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Opis bibliograficzny
Główni autorzy: Haskill, J. S., Elliott, B. E., Kerbel, R., Axelrad, M. A., Eidinger, D.
Format: Artykuł
Język:English
Wydane: The Rockefeller University Press 1972
Hasła przedmiotowe:
Brief Definitive Reports
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139165/
https://ncbi.nlm.nih.gov/pubmed/4554454
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Opis
Streszczenie:Antigen-binding cells of T and B origin can readily be determined by quantitating the number of sheep erythrocytes per rosette after glutaraldehyde fixation. The T(1) and T(2) populations have low antigen-binding properties and are very unstable without fixation. The B(1) and B(2) populations are stable and correlate with precursor and secretory cells. Fixation of rosettes permits a sensitive test for studying differentiation of T and B cells.

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