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PRODUCTION OF TL ANTIBODY BY MICE IMMUNIZED WITH TL(-) CELL POPULATIONS : A POSSIBLE ASSAY FOR THYMIC HORMONE

TL(-) mice make TL antibody when immunized with spleen or bone marrow cells from TL(+) donors, despite the fact that these cells do not express TL antigen. This has been shown to depend on maturation of TL(-) precursors, contained in the inoculum, into TL(+) cells under influence of the recipient�...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Komuro, Katsutoshi, Boyse, Edward A., Old, Lloyd J.
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: The Rockefeller University Press 1973
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139483/
https://ncbi.nlm.nih.gov/pubmed/4685707
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Yhteenveto:TL(-) mice make TL antibody when immunized with spleen or bone marrow cells from TL(+) donors, despite the fact that these cells do not express TL antigen. This has been shown to depend on maturation of TL(-) precursors, contained in the inoculum, into TL(+) cells under influence of the recipient's thymus; the differentiated TL(+) cells then evoke production of TL antibody.