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Inactivation of Lrg-47 and Irg-47 Reveals a Family of Interferon γ–Inducible Genes with Essential, Pathogen-Specific Roles in Resistance to Infection
The cytokine interferon (IFN)-γ regulates immune clearance of parasitic, bacterial, and viral infections; however, the underlying mechanisms are poorly understood. Recently, a family of IFN-γ–induced genes has been identified that encode 48-kD GTP-binding proteins that localize to the endoplasmic re...
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| Автори: | , , , , , , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
The Rockefeller University Press
2001
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2193451/ https://ncbi.nlm.nih.gov/pubmed/11457893 |
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