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Prevalence and associations of asymptomatic retinal emboli in Latinos: The Los Angeles Latino Eye Study (LALES)

PURPOSE: To study the prevalence and associations of asymptomatic retinal emboli in a cohort of Latinos, and compare these findings to those of previous population studies. DESIGN: Population-based cross-sectional study METHODS: All participants in this study underwent a comprehensive eye exam, incl...

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Detalhes bibliográficos
Main Authors: Hoki, Susan Liu, Varma, Rohit, Lai, Mei Ying, Azen, Stanley P, Klein, Ronald
Formato: Artigo
Idioma:English
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219465/
https://ncbi.nlm.nih.gov/pubmed/17981255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajo.2007.08.030
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Descrição
Resumo:PURPOSE: To study the prevalence and associations of asymptomatic retinal emboli in a cohort of Latinos, and compare these findings to those of previous population studies. DESIGN: Population-based cross-sectional study METHODS: All participants in this study underwent a comprehensive eye exam, including fundus photography. Photographs were graded by trained masked graders. Lifestyle factors and medical history were obtained during extensive interviews. Blood pressure, serum glucose, and glycosylated hemoglobin were measured. Age and gender-specific prevalence rates were calculated. Odds Ratios (OR) were calculated using stepwise logistic regression analyses to identify independent risk factor associations with asymptomatic retinal emboli. RESULTS: Photographs gradable for retinal emboli were obtained from 5959 participants. For all participants, the prevalence of definite asymptomatic retinal emboli was 0.4% (n=26). Stepwise logistic regression analyses identified smoking (>5 pack years) (OR=4.3) and history of coronary artery disease (OR=2.8) to be independently associated with retinal emboli (P<0.05). CONCLUSION: We found a lower prevalence of asymptomatic retinal emboli compared to previous population-based studies. This could be secondary to the LALES population being younger, having lower blood pressure, and fewer smokers than other studies. As in other studies, smoking emerges as the strongest association with retinal emboli.