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The cGMP-phosphodiesterase and its contribution to sensitivity regulation in retinal rods
We have used the truncated outer segment preparation to measure rod cGMP-phosphodiesterase activity, as well as its modulation by Ca2+, in darkness and in light. The basal enzyme activity in darkness was approximately 0-3 s-1, and was largely independent of Ca2+ concentration from 10 nM to 10 microM...
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| Format: | Artigo |
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| Sprog: | English |
| Udgivet: |
The Rockefeller University Press
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229286/ https://ncbi.nlm.nih.gov/pubmed/8648297 |
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