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TOPK Phosphorylation of Histone H2AX Prevents Arsenite-Induced Apoptosis in RPMI7951 Melanoma Cells
PURPOSE: Arsenic is a valuable therapeutic tool in cancer treatment. T-LAK cell-originated protein kinase (TOPK) is highly expressed in cancer cells but its specific function is still unknown. We investigated the role of TOPK in arsenic-induced apoptosis in RPMI7951 human melanoma cells. EXPERIMENTA...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238807/ https://ncbi.nlm.nih.gov/pubmed/17145805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-0410 |
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