A BAC clone fingerprinting approach to the detection of human genome rearrangements

We present a method, called fingerprint profiling (FPP), that uses restriction digest fingerprints of bacterial artificial chromosome clones to detect and classify rearrangements in the human genome. The approach uses alignment of experimental fingerprint patterns to in silico digests of the sequenc...

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Hauptverfasser: Krzywinski, Martin, Bosdet, Ian, Mathewson, Carrie, Wye, Natasja, Brebner, Jay, Chiu, Readman, Corbett, Richard, Field, Matthew, Lee, Darlene, Pugh, Trevor, Volik, Stas, Siddiqui, Asim, Jones, Steven, Schein, Jacquie, Collins, Collin, Marra, Marco
Format: Artikel
Sprache:English
Veröffentlicht: BioMed Central 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246298/
https://ncbi.nlm.nih.gov/pubmed/17953769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-10-r224
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2246298/
https://ncbi.nlm.nih.gov/pubmed/17953769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-10-r224

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