Herpes Simplex Virus Type 1 DNA Is Immunostimulatory In Vitro and In Vivo

Recently, prokaryotic DNAs containing unmethylated CpG motifs have been shown to be intrinsically immunostimulatory both in vitro and in vivo, tending to promote Th1-like responses. In contrast, CpG dinucleotides in mammalian DNAs are extensively methylated on cytosines and hence immunologically ine...

Full description

Saved in:
Bibliographic Details
Main Authors: Lundberg, Patric, Welander, Paula, Han, Xiao, Cantin, Edouard
Format: Article
Language:en
Published: American Society for Microbiology 2003
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC225007/
https://ncbi.nlm.nih.gov/pubmed/14512563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.11158-11169.2003
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC225007/
https://ncbi.nlm.nih.gov/pubmed/14512563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.11158-11169.2003

Similar Items