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Unique MAP Kinase Binding Sites
Map kinases are drug targets for autoimmune disease, cancer, and apoptosis-related diseases. Drug discovery efforts have developed MAP kinase inhibitors directed toward the ATP binding site and neighboring “DFG-out” site, both of which are targets for inhibitors of other protein kinases. On the othe...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | English |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266891/ https://ncbi.nlm.nih.gov/pubmed/18068683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2007.09.016 |
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