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Failure to detect abnormal prion protein and scrapie-associated fibrils 6 wk after intracerebral inoculation of genetically susceptible sheep with scrapie agent
Detection of the scrapie-associated protease-resistant prion protein (PrP(res)) in sheep brains in the early phase after intracerebral inoculation of the scrapie agent has not been documented. Fourteen 4-mo-old, genetically susceptible lambs (QQ homozygous at codon 171 of the PrP gene) were obtained...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado: |
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC227019/ https://ncbi.nlm.nih.gov/pubmed/12418787 |
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