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Regulation of the calcium release channel from rabbit skeletal muscle by the nucleotides ATP, AMP, IMP and adenosine

1. Nucleotide activation of skeletal muscle ryanodine receptors (RyRs) was studied in planar lipid bilayers in order to understand RyR regulation in vivo under normal and fatigued conditions. With ‘resting’ calcium (100 nm cytoplasmic and 1 mm luminal), RyRs had an open probability (P(o)) of ∼0.01 i...

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Hlavní autoři: Laver, Derek R, Lenz, Gerlinde K E, Lamb, Graham D
Médium: Článek
Jazyk:English
Vydáno: Blackwell Science Inc 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279010/
https://ncbi.nlm.nih.gov/pubmed/11744753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.00763.x
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