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In vitro selection of a 7-methyl-guanosine binding RNA that inhibits translation of capped mRNA molecules
Using systematic evolution of ligands by exponential enrichment (SELEX), an RNA molecule was isolated that displays a 1,000-fold higher affinity for guanosine residues that carry an N-7 methyl group than for nonmethylated guanosine residues. The methylated guanosine residue closely resembles the 5′...
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| Príomhchruthaitheoirí: | , |
|---|---|
| Formáid: | Alt |
| Teanga: | en |
| Foilsithe / Cruthaithe: |
The National Academy of Sciences of the USA
1997
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC22984/ https://ncbi.nlm.nih.gov/pubmed/9238009 |
| Clibeanna: |
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