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The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome

Processing of antigens for presentation by major histocompatibility complex (MHC) class I molecules requires the activity of the proteasome. The 20S proteasome complex is composed of 14 different subunits, 2 of which can be substituted by the interferon γ (IFN-γ)-inducible and MHC-encoded subunits L...

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Autori principali: Groettrup, Marcus, Standera, Sybille, Stohwasser, Ralf, Kloetzel, Peter M.
Natura: Articolo
Lingua:en
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC22989/
https://ncbi.nlm.nih.gov/pubmed/9256419
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