Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers

Aberrant DNA methylation is a common phenomenon in human cancer, but its patterns, causes, and consequences are poorly defined. Promoter methylation of the DNA mismatch repair gene MutL homologue (MLH1) has been implicated in the subset of colorectal cancers that shows microsatellite instability (MS...

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Autori principali: Kuismanen, Shannon A., Holmberg, Mari T., Salovaara, Reijo, Schweizer, Pascal, Aaltonen, Lauri A., de la Chapelle, Albert, Nyström-Lahti, Minna, Peltomäki, Päivi
Natura: Articolo
Lingua:en
Pubblicazione: The National Academy of Sciences 1999
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC23037/
https://ncbi.nlm.nih.gov/pubmed/10535979
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https://ncbi.nlm.nih.gov/pmc/articles/PMC23037/
https://ncbi.nlm.nih.gov/pubmed/10535979

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