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Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

Damage from free radicals has been demonstrated in susceptible neuronal populations in cases of Alzheimer disease. In this study, we investigated whether iron, a potent source of the highly reactive hydroxyl radical that is generated by the Fenton reaction with H(2)O(2), might contribute to the sour...

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Autori principali: Smith, Mark A., Harris, Peggy L. R., Sayre, Lawrence M., Perry, George
Natura: Articolo
Lingua:en
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC23283/
https://ncbi.nlm.nih.gov/pubmed/9275217
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