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Coupled movement of permeant and blocking ions in the CFTR chloride channel pore

The cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel pore is blocked in a voltage-dependent manner by a broad range of anionic substances added to the cytoplasmic side of the membrane. Here we investigate the origin of the voltage dependence of block by intracellular Au(CN)(2...

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Bibliografiske detaljer
Main Authors: Gong, Xiandi, Linsdell, Paul
Format: Artigo
Sprog:English
Udgivet: Blackwell Science Inc 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342964/
https://ncbi.nlm.nih.gov/pubmed/12679371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.038216
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