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Cetuximab potentiates oxaliplatin cytotoxic effect through a defect in NER and DNA replication initiation
Preclinical studies have demonstrated that the chemotherapeutic action of oxaliplatin, a third generation platinum derivative, is improved when combined with cetuximab, a monoclonal antibody inhibitor of epidermal growth factor receptors. To explore the mechanism of this synergistic benefit, we used...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Nature Publishing Group
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2359709/ https://ncbi.nlm.nih.gov/pubmed/18182978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604134 |
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