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Phentolamine block of K(ATP) channels is mediated by Kir6.2

The ATP-sensitive K(+)-channel (K(ATP) channel) plays a key role in insulin secretion from pancreatic β cells. It is closed both by glucose metabolism and the sulfonylurea drugs that are used in the treatment of noninsulin-dependent diabetes mellitus, thereby initiating a membrane depolarization tha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Proks, Peter, Ashcroft, Frances M.
Formatua: Artikulua
Hizkuntza:en
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC23609/
https://ncbi.nlm.nih.gov/pubmed/9326676
Etiketak: Etiketa erantsi
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