Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agents

Mismatch DNA repair deficiency is associated with resistance to certain major groove alkylating agents including methylating agents and cisplatin. We have now studied the relevance of mismatch repair alterations to the cytotoxicity induced by drugs which alkylate N3 adenines in the minor groove of D...

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Bibliografiske detaljer
Main Authors: Colella, G, Marchini, S, D'Incalci, M, Brown, R, Broggini, M
Format: Artigo
Sprog:English
Udgivet: Nature Publishing Group 1999
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362350/
https://ncbi.nlm.nih.gov/pubmed/10408835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690360
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC2362350/
https://ncbi.nlm.nih.gov/pubmed/10408835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690360

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