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HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling
Mutant presenilins have been found to cause Alzheimer disease. Here, we describe the identification and characterization of HOP-1, a Caenorhabditis elegans presenilin that displays much more lower sequence identity with human presenilins than does the other C. elegans presenilin, SEL-12. Despite con...
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| Hauptverfasser: | , |
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| Format: | Artikel |
| Sprache: | en |
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The National Academy of Sciences of the USA
1997
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23751/ https://ncbi.nlm.nih.gov/pubmed/9342387 |
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