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Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney
Activation-induced DNA cytosine deaminase (AID) is required for somatic hypermutation (SHM) and efficient class switch recombination (CSR) of immunoglobulin (Ig) genes. We created AID-transgenic mice that express AID ubiquitously under the control of a β–actin promoter. When crossed with AID−/− mice...
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| Autori principali: | , , , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2376253/ https://ncbi.nlm.nih.gov/pubmed/18067961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.10.041 |
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