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Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.

Mutagenesis studies indicated that the three cytoplasmic cysteines of the influenza virus A/Japan/305/57 hemagglutinin (HA) are all palmitylated, but to an unequal extent. Replacement of all three cysteines abolished palmitylation, but affected neither HA biosynthesis nor function. Palmitate was not...

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Manylion Llyfryddiaeth
Prif Awduron: Naim, H Y, Amarneh, B, Ktistakis, N T, Roth, M G
Fformat: Erthygl
Iaith:en
Cyhoeddwyd: 1992
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC240475/
https://ncbi.nlm.nih.gov/pubmed/1433532
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id pubmed-240475
record_format dspace
spelling pubmed-2404752003-12-01 Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin. Naim, H Y Amarneh, B Ktistakis, N T Roth, M G J Virol Research Article Mutagenesis studies indicated that the three cytoplasmic cysteines of the influenza virus A/Japan/305/57 hemagglutinin (HA) are all palmitylated, but to an unequal extent. Replacement of all three cysteines abolished palmitylation, but affected neither HA biosynthesis nor function. Palmitate was not required for HA to be incorporated into virions. 1992-12 /pmc/articles/PMC240475/ /pubmed/1433532 Text en
institution US National Library of Medicine
collection PubMed Central
language en
format Article
topic Research Article
spellingShingle Research Article
Naim, H Y
Amarneh, B
Ktistakis, N T
Roth, M G
Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.
description Mutagenesis studies indicated that the three cytoplasmic cysteines of the influenza virus A/Japan/305/57 hemagglutinin (HA) are all palmitylated, but to an unequal extent. Replacement of all three cysteines abolished palmitylation, but affected neither HA biosynthesis nor function. Palmitate was not required for HA to be incorporated into virions.
author Naim, H Y
Amarneh, B
Ktistakis, N T
Roth, M G
author_facet Naim, H Y
Amarneh, B
Ktistakis, N T
Roth, M G
author_sort Naim, H Y
title Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.
title_short Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.
title_full Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.
title_fullStr Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.
title_full_unstemmed Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.
title_sort effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.
publishDate 1992
url https://ncbi.nlm.nih.gov/pmc/articles/PMC240475/
https://ncbi.nlm.nih.gov/pubmed/1433532
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