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Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin.
Mutagenesis studies indicated that the three cytoplasmic cysteines of the influenza virus A/Japan/305/57 hemagglutinin (HA) are all palmitylated, but to an unequal extent. Replacement of all three cysteines abolished palmitylation, but affected neither HA biosynthesis nor function. Palmitate was not...
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1992
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC240475/ https://ncbi.nlm.nih.gov/pubmed/1433532 |
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pubmed-2404752003-12-01 Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin. Naim, H Y Amarneh, B Ktistakis, N T Roth, M G J Virol Research Article Mutagenesis studies indicated that the three cytoplasmic cysteines of the influenza virus A/Japan/305/57 hemagglutinin (HA) are all palmitylated, but to an unequal extent. Replacement of all three cysteines abolished palmitylation, but affected neither HA biosynthesis nor function. Palmitate was not required for HA to be incorporated into virions. 1992-12 /pmc/articles/PMC240475/ /pubmed/1433532 Text en |
| institution |
US National Library of Medicine |
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PubMed Central |
| language |
en |
| format |
Article |
| topic |
Research Article |
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Research Article Naim, H Y Amarneh, B Ktistakis, N T Roth, M G Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin. |
| description |
Mutagenesis studies indicated that the three cytoplasmic cysteines of the influenza virus A/Japan/305/57 hemagglutinin (HA) are all palmitylated, but to an unequal extent. Replacement of all three cysteines abolished palmitylation, but affected neither HA biosynthesis nor function. Palmitate was not required for HA to be incorporated into virions. |
| author |
Naim, H Y Amarneh, B Ktistakis, N T Roth, M G |
| author_facet |
Naim, H Y Amarneh, B Ktistakis, N T Roth, M G |
| author_sort |
Naim, H Y |
| title |
Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin. |
| title_short |
Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin. |
| title_full |
Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin. |
| title_fullStr |
Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin. |
| title_full_unstemmed |
Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin. |
| title_sort |
effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin. |
| publishDate |
1992 |
| url |
https://ncbi.nlm.nih.gov/pmc/articles/PMC240475/ https://ncbi.nlm.nih.gov/pubmed/1433532 |
| _version_ |
1759048012392300544 |