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Antiangiogenic activity of aplidine, a new agent of marine origin

The antineoplastic compound aplidine, a new marine-derived depsipeptide, has shown preclinical activity in vitro on haematological and solid tumour cell lines. It is currently in early phase clinical trials. The exact mechanism of action of this anticancer agent still needs to be clarified. We have...

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Autors principals: Taraboletti, G, Poli, M, Dossi, R, Manenti, L, Borsotti, P, Faircloth, G T, Broggini, M, D'Incalci, M, Ribatti, D, Giavazzi, R
Format: Article
Idioma:English
Publicat: Nature Publishing Group 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409535/
https://ncbi.nlm.nih.gov/pubmed/15173857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601864
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