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Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7
Ubiquitination is a posttranslational mechanism that controls diverse cellular processes. We focus here on the ubiquitin ligase Fbw7, a recently identified hematopoietic tumor suppressor that can target for degradation several important oncogenes, including Notch1, c-Myc, and cyclin E. We have gener...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
The Rockefeller University Press
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2413036/ https://ncbi.nlm.nih.gov/pubmed/18474632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080277 |
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