Swine Genome Sequencing Consortium (SGSC): A Strategic Roadmap for Sequencing The Pig Genome

The Swine Genome Sequencing Consortium (SGSC) was formed in September 2003 by academic, government and industry representatives to provide international coordination for sequencing the pig genome. The SGSC’s mission is to advance biomedical research for animal production and health by the developmen...

詳細記述

保存先:
書誌詳細
主要な著者: Schook, Lawrence B., Beever, Jonathan E., Rogers, Jane, Humphray, Sean, Archibald, Alan, Chardon, Patrick, Milan, Denis, Rohrer, Gary, Eversole, Kellye
フォーマット: 論文
言語:English
出版事項: Hindawi Publishing Corporation 2005
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447480/
https://ncbi.nlm.nih.gov/pubmed/18629187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cfg.479
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
id pubmed-2447480
record_format dspace
spelling pubmed-24474802008-07-14 Swine Genome Sequencing Consortium (SGSC): A Strategic Roadmap for Sequencing The Pig Genome Schook, Lawrence B. Beever, Jonathan E. Rogers, Jane Humphray, Sean Archibald, Alan Chardon, Patrick Milan, Denis Rohrer, Gary Eversole, Kellye Comp Funct Genomics Research Article The Swine Genome Sequencing Consortium (SGSC) was formed in September 2003 by academic, government and industry representatives to provide international coordination for sequencing the pig genome. The SGSC’s mission is to advance biomedical research for animal production and health by the development of DNAbased tools and products resulting from the sequencing of the swine genome. During the past 2 years, the SGSC has met bi-annually to develop a strategic roadmap for creating the required scientific resources, to integrate existing physical maps, and to create a sequencing strategy that captured international participation and a broad funding base. During the past year, SGSC members have integrated their respective physical mapping data with the goal of creating a minimal tiling path (MTP) that will be used as the sequencing template. During the recent Plant and Animal Genome meeting (January 16, 2005 San Diego, CA), presentations demonstrated that a human–pig comparative map has been completed, BAC fingerprint contigs (FPC) for each of the autosomes and X chromosome have been constructed and that BAC end-sequencing has permitted, through BLAST analysis and RH-mapping, anchoring of the contigs. Thus, significant progress has been made towards the creation of a MTP. In addition, whole-genome (WG) shotgun libraries have been constructed and are currently being sequenced in various laboratories around the globe. Thus, a hybrid sequencing approach in which 3x coverage of BACs comprising the MTP and 3x of the WG-shotgun libraries will be used to develop a draft 6x coverage of the pig genome. Hindawi Publishing Corporation 2005-06 /pmc/articles/PMC2447480/ /pubmed/18629187 http://dx.doi.org/10.1002/cfg.479 Text en Copyright © 2005 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
institution US National Library of Medicine
collection PubMed Central
language English
format Article
topic Research Article
spellingShingle Research Article
Schook, Lawrence B.
Beever, Jonathan E.
Rogers, Jane
Humphray, Sean
Archibald, Alan
Chardon, Patrick
Milan, Denis
Rohrer, Gary
Eversole, Kellye
Swine Genome Sequencing Consortium (SGSC): A Strategic Roadmap for Sequencing The Pig Genome
description The Swine Genome Sequencing Consortium (SGSC) was formed in September 2003 by academic, government and industry representatives to provide international coordination for sequencing the pig genome. The SGSC’s mission is to advance biomedical research for animal production and health by the development of DNAbased tools and products resulting from the sequencing of the swine genome. During the past 2 years, the SGSC has met bi-annually to develop a strategic roadmap for creating the required scientific resources, to integrate existing physical maps, and to create a sequencing strategy that captured international participation and a broad funding base. During the past year, SGSC members have integrated their respective physical mapping data with the goal of creating a minimal tiling path (MTP) that will be used as the sequencing template. During the recent Plant and Animal Genome meeting (January 16, 2005 San Diego, CA), presentations demonstrated that a human–pig comparative map has been completed, BAC fingerprint contigs (FPC) for each of the autosomes and X chromosome have been constructed and that BAC end-sequencing has permitted, through BLAST analysis and RH-mapping, anchoring of the contigs. Thus, significant progress has been made towards the creation of a MTP. In addition, whole-genome (WG) shotgun libraries have been constructed and are currently being sequenced in various laboratories around the globe. Thus, a hybrid sequencing approach in which 3x coverage of BACs comprising the MTP and 3x of the WG-shotgun libraries will be used to develop a draft 6x coverage of the pig genome.
author Schook, Lawrence B.
Beever, Jonathan E.
Rogers, Jane
Humphray, Sean
Archibald, Alan
Chardon, Patrick
Milan, Denis
Rohrer, Gary
Eversole, Kellye
author_facet Schook, Lawrence B.
Beever, Jonathan E.
Rogers, Jane
Humphray, Sean
Archibald, Alan
Chardon, Patrick
Milan, Denis
Rohrer, Gary
Eversole, Kellye
author_sort Schook, Lawrence B.
title Swine Genome Sequencing Consortium (SGSC): A Strategic Roadmap for Sequencing The Pig Genome
title_short Swine Genome Sequencing Consortium (SGSC): A Strategic Roadmap for Sequencing The Pig Genome
title_full Swine Genome Sequencing Consortium (SGSC): A Strategic Roadmap for Sequencing The Pig Genome
title_fullStr Swine Genome Sequencing Consortium (SGSC): A Strategic Roadmap for Sequencing The Pig Genome
title_full_unstemmed Swine Genome Sequencing Consortium (SGSC): A Strategic Roadmap for Sequencing The Pig Genome
title_sort swine genome sequencing consortium (sgsc): a strategic roadmap for sequencing the pig genome
publisher Hindawi Publishing Corporation
publisher_facet Hindawi Publishing Corporation
publishDate 2005
url https://ncbi.nlm.nih.gov/pmc/articles/PMC2447480/
https://ncbi.nlm.nih.gov/pubmed/18629187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cfg.479
_version_ 1760723019251056640

類似資料