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Mannitol Uptake by Saccharomyces cerevisiae

The uptake of mannitol, a nonmetabolized hexitol, by Saccharomyces cerevisiae was measured. Various characteristics examined include: effects of temperature on uptake, inhibition of uptake by uranyl nitrate, competition for uptake by glucose, counterflow of mannitol by glucose, and the affinity of m...

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Huvudupphovsmän: Maxwell, W. A., Spoerl, Edward
Materialtyp: Artikel
Språk:en
Publicerad: 1971
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC248497/
https://ncbi.nlm.nih.gov/pubmed/5547989
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spelling pubmed-2484972003-12-16 Mannitol Uptake by Saccharomyces cerevisiae Maxwell, W. A. Spoerl, Edward J Bacteriol Physiology and Metabolism The uptake of mannitol, a nonmetabolized hexitol, by Saccharomyces cerevisiae was measured. Various characteristics examined include: effects of temperature on uptake, inhibition of uptake by uranyl nitrate, competition for uptake by glucose, counterflow of mannitol by glucose, and the affinity of mannitol for a carrier system as measured by a Michaelis constant. That energy is required for uptake was shown by a decreased uptake in the presence of energy inhibitors, by an increased uptake upon addition of energy sources, and by the absence of uptake under anaerobic conditions with no fermentable energy sources available. That mannitol is bound to some cellular constituent after it enters the cell was shown by its attachment to non-dialyzable cell fragments and by the lack of an osmotic response, both of which are consistent with a minimal efflux. 1971-03 /pmc/articles/PMC248497/ /pubmed/5547989 Text en Copyright © 1971 American Society for Microbiology
institution US National Library of Medicine
collection PubMed Central
language en
format Article
topic Physiology and Metabolism
spellingShingle Physiology and Metabolism
Maxwell, W. A.
Spoerl, Edward
Mannitol Uptake by Saccharomyces cerevisiae
description The uptake of mannitol, a nonmetabolized hexitol, by Saccharomyces cerevisiae was measured. Various characteristics examined include: effects of temperature on uptake, inhibition of uptake by uranyl nitrate, competition for uptake by glucose, counterflow of mannitol by glucose, and the affinity of mannitol for a carrier system as measured by a Michaelis constant. That energy is required for uptake was shown by a decreased uptake in the presence of energy inhibitors, by an increased uptake upon addition of energy sources, and by the absence of uptake under anaerobic conditions with no fermentable energy sources available. That mannitol is bound to some cellular constituent after it enters the cell was shown by its attachment to non-dialyzable cell fragments and by the lack of an osmotic response, both of which are consistent with a minimal efflux.
author Maxwell, W. A.
Spoerl, Edward
author_facet Maxwell, W. A.
Spoerl, Edward
author_sort Maxwell, W. A.
title Mannitol Uptake by Saccharomyces cerevisiae
title_short Mannitol Uptake by Saccharomyces cerevisiae
title_full Mannitol Uptake by Saccharomyces cerevisiae
title_fullStr Mannitol Uptake by Saccharomyces cerevisiae
title_full_unstemmed Mannitol Uptake by Saccharomyces cerevisiae
title_sort mannitol uptake by saccharomyces cerevisiae
publishDate 1971
url https://ncbi.nlm.nih.gov/pmc/articles/PMC248497/
https://ncbi.nlm.nih.gov/pubmed/5547989
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