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Reversibility of Aberrant Global DNA and Estrogen Receptor-α Gene Methylation Distinguishes Colorectal Precancer from Cancer

Alterations in the global methylation of DNA and in specific regulatory genes are two epigenetic alterations found in cancer. However, the significance of epigenetic changes for diagnosis and/or prognosis of colorectal cancer have not been established, although it has been extensively investigated....

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Autors principals: Shen, Rulong, Tao, Lianhui, Xu, Yiqing, Chang, Shi, Van Brocklyn, James, Gao, Jian-Xin
Format: Article
Idioma:English
Publicat: e-Century Publishing Corporation 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491387/
https://ncbi.nlm.nih.gov/pubmed/18830381
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