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DOMINANT NEGATIVE MUTANTS OF TRANSDUCIN-α THAT BLOCK ACTIVATED RECEPTOR
Mutations counterpart to dominant negative RasSer17Asn in the α-subunits of heterotrimeric G-proteins are known to also produce dominant negative effects. The mechanism of these mutations remains poorly understood. Here, we examined the effects and mechanism of the Ser43Cys and Ser43Asn mutants of t...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525804/ https://ncbi.nlm.nih.gov/pubmed/16700559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060381e |
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