Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors

Integration of viral DNA into the host chromosome is an essential step in the life cycle of retroviruses and is facilitated by the viral integrase enzyme. The first generation of integrase inhibitors recently approved or currently in late-stage clinical trials shows great promise for the treatment o...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Goethals, Olivia, Clayton, Reginald, Van Ginderen, Marcia, Vereycken, Inge, Wagemans, Elisabeth, Geluykens, Peggy, Dockx, Koen, Strijbos, Rudy, Smits, Veerle, Vos, Ann, Meersseman, Geert, Jochmans, Dirk, Vermeire, Kurt, Schols, Dominique, Hallenberger, Sabine, Hertogs, Kurt
التنسيق: مقال
اللغة:English
منشور في: American Society for Microbiology (ASM) 2008
الموضوعات:
Vaccines and Antiviral Agents
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573211/
https://ncbi.nlm.nih.gov/pubmed/18715920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00470-08
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الانترنت

https://ncbi.nlm.nih.gov/pmc/articles/PMC2573211/
https://ncbi.nlm.nih.gov/pubmed/18715920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00470-08

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