In vivo BLyS/BAFF Neutralization Ameliorates Islet-Directed Autoimmunity in Non-Obese Diabetic (NOD) Mice

B-lymphocytes are required for the pathogenesis of autoimmune diabetes in NOD mice. Previous studies established that a lymphopenic transitional (TR) B-cell compartment reduces the competitive constraint on the entry of newly emerging TR B-cells into the splenic follicle (FO), thereby disrupting a p...

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Main Authors: Zekavat, Ghazal, Rostami, Susan Y., Badkerhanian, Armen, Parsons, Ronald F., Koeberlein, Brigitte, Yu, Ming, Ward, Christopher D., Migone, Thi-Sau, Yu, Liping, Eisenbarth, George S., Cancro, Michael P., Naji, Ali, Noorchashm, Hooman
Format: Artigo
Sprog:English
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586964/
https://ncbi.nlm.nih.gov/pubmed/19018006
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2586964/
https://ncbi.nlm.nih.gov/pubmed/19018006

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