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Translesion Synthesis past Tamoxifen-derived DNA Adducts by Human DNA Polymerases η and κ
The long-term treatment of tamoxifen (TAM), widely used for adjuvant chemotherapy and chemoprevention for breast cancer, increases a risk of developing endometrial cancer. A high frequency of K-ras mutations has been observed in the endometrium of women treated with TAM. Human DNA polymerase (pol) η...
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| 主要な著者: | , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593916/ https://ncbi.nlm.nih.gov/pubmed/17002316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0608461 |
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