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A Conserved Telomerase Motif within the Catalytic Domain of Telomerase Reverse Transcriptase Is Specifically Required for Repeat Addition Processivity
Telomerase is a ribonucleoprotein reverse transcriptase responsible for the maintenance of one strand of the telomere terminal repeats. The catalytic protein subunit of the telomerase complex, known as TERT, possesses a reverse transcriptase (RT) domain that mediates nucleotide addition. The RT doma...
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| Médium: | Článek |
| Jazyk: | en |
| Vydáno: |
American Society for Microbiology
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC262686/ https://ncbi.nlm.nih.gov/pubmed/14612390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8440-8449.2003 |
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