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A Systematic Evaluation of the Function of the Protein-Remodeling Factor Hsp104 in [PSI(+)] Prion Propagation in S. cerevisiae by Comprehensive Chromosomal Mutations

The yeast prion [PSI(+)] represents an aggregated state of the translational release factor Sup35 (eRF3) and deprives termination complexes of functional Sup35, resulting in nonsense codon suppression. Protein-remodeling factor Hsp104 is involved in thermotolerance and [PSI(+)] propagation, however...

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Auteurs principaux: Takahashi, Aiko, Hara, Hideyuki, Kurahashi, Hiroshi, Nakamura, Yoshikazu
Format: Article
Langue:English
Publié: Landes Bioscience 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633711/
https://ncbi.nlm.nih.gov/pubmed/19164920
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