A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation

A FITC-induced allergic contact hypersensitivity model was used to investigate the role that the prostaglandin D(2) receptor–chemoattractant receptor-homologous molecule expressed on T(h)2 cells (CRTH2) plays in modulating cutaneous inflammation. Our results show that inhibition of CRTH2, achieved v...

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Autori principali: Boehme, Stefen A., Franz-Bacon, Karin, Chen, Edward P., Šášik, Roman, Sprague, L. James, Ly, Tai Wei, Hardiman, Gary, Bacon, Kevin B.
Natura: Articolo
Lingua:English
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638841/
https://ncbi.nlm.nih.gov/pubmed/19066314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxn127
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Accesso online

https://ncbi.nlm.nih.gov/pmc/articles/PMC2638841/
https://ncbi.nlm.nih.gov/pubmed/19066314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxn127

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