Protective HLA Class I Alleles That Restrict Acute-Phase CD8(+) T-Cell Responses Are Associated with Viral Escape Mutations Located in Highly Conserved Regions of Human Immunodeficiency Virus Type 1

The control of human immunodeficiency virus type 1 (HIV-1) associated with particular HLA class I alleles suggests that some CD8(+) T-cell responses may be more effective than others at containing HIV-1. Unfortunately, substantial diversities in the breadth, magnitude, and function of these response...

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Autori principali: Wang, Yaoyu E., Li, Bin, Carlson, Jonathan M., Streeck, Hendrik, Gladden, Adrianne D., Goodman, Robert, Schneidewind, Arne, Power, Karen A., Toth, Ildiko, Frahm, Nicole, Alter, Galit, Brander, Christian, Carrington, Mary, Walker, Bruce D., Altfeld, Marcus, Heckerman, David, Allen, Todd M.
Natura: Articolo
Lingua:English
Pubblicazione: American Society for Microbiology (ASM) 2009
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643763/
https://ncbi.nlm.nih.gov/pubmed/19036810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01061-08
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Accesso online

https://ncbi.nlm.nih.gov/pmc/articles/PMC2643763/
https://ncbi.nlm.nih.gov/pubmed/19036810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01061-08

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