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Characterization of Relaxin Receptor (RXFP1) Desensitization and Internalization in Primary Human Decidual Cells and RXFP1-Transfected HEK293 Cells

We report here the desensitization and internalization of the relaxin receptor (RXFP1) after agonist activation in both primary human decidual cells and HEK293 cells stably transfected with RXFP1. The importance of β-arrestin 2 in these processes has also been demonstrated. Thus, in HEK-RXFP1 cells...

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Библиографические подробности
Главные авторы: Kern, András, Bryant-Greenwood, Gillian D.
Формат: Статья
Язык:English
Опубликовано: The Endocrine Society 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671891/
https://ncbi.nlm.nih.gov/pubmed/19116340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1385
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