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Male-pattern baldness susceptibility locus at 20p11
We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 × 10(−14) for rs1160312). The one man in seven who harbors risk alleles at both 20p1...
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
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2008
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| Những chủ đề: | |
| Truy cập trực tuyến: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672151/ https://ncbi.nlm.nih.gov/pubmed/18849991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.255 |
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pubmed-26721512009-05-01 Male-pattern baldness susceptibility locus at 20p11 Richards, J Brent Yuan, Xin Geller, Frank Waterworth, Dawn Bataille, Veronique Glass, Daniel Song, Kijoung Waeber, Gerard Vollenweider, Peter Aben, Katja K H Kiemeney, Lambertus A Walters, Bragi Soranzo, Nicole Thorsteinsdottir, Unnur Kong, Augustine Rafnar, Thorunn Deloukas, Panos Sulem, Patrick Stefansson, Hreinn Stefansson, Kari Spector, Tim D Mooser, Vincent Nat Genet Article We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 × 10(−14) for rs1160312). The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 × 10(−15)). 2008-10-12 2008-11 /pmc/articles/PMC2672151/ /pubmed/18849991 http://dx.doi.org/10.1038/ng.255 Text en © 2008 Nature Publishing Group |
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US National Library of Medicine |
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PubMed Central |
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English |
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Article |
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Article |
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Article Richards, J Brent Yuan, Xin Geller, Frank Waterworth, Dawn Bataille, Veronique Glass, Daniel Song, Kijoung Waeber, Gerard Vollenweider, Peter Aben, Katja K H Kiemeney, Lambertus A Walters, Bragi Soranzo, Nicole Thorsteinsdottir, Unnur Kong, Augustine Rafnar, Thorunn Deloukas, Panos Sulem, Patrick Stefansson, Hreinn Stefansson, Kari Spector, Tim D Mooser, Vincent Male-pattern baldness susceptibility locus at 20p11 |
| description |
We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 × 10(−14) for rs1160312). The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 × 10(−15)). |
| author |
Richards, J Brent Yuan, Xin Geller, Frank Waterworth, Dawn Bataille, Veronique Glass, Daniel Song, Kijoung Waeber, Gerard Vollenweider, Peter Aben, Katja K H Kiemeney, Lambertus A Walters, Bragi Soranzo, Nicole Thorsteinsdottir, Unnur Kong, Augustine Rafnar, Thorunn Deloukas, Panos Sulem, Patrick Stefansson, Hreinn Stefansson, Kari Spector, Tim D Mooser, Vincent |
| author_facet |
Richards, J Brent Yuan, Xin Geller, Frank Waterworth, Dawn Bataille, Veronique Glass, Daniel Song, Kijoung Waeber, Gerard Vollenweider, Peter Aben, Katja K H Kiemeney, Lambertus A Walters, Bragi Soranzo, Nicole Thorsteinsdottir, Unnur Kong, Augustine Rafnar, Thorunn Deloukas, Panos Sulem, Patrick Stefansson, Hreinn Stefansson, Kari Spector, Tim D Mooser, Vincent |
| author_sort |
Richards, J Brent |
| title |
Male-pattern baldness susceptibility locus at 20p11 |
| title_short |
Male-pattern baldness susceptibility locus at 20p11 |
| title_full |
Male-pattern baldness susceptibility locus at 20p11 |
| title_fullStr |
Male-pattern baldness susceptibility locus at 20p11 |
| title_full_unstemmed |
Male-pattern baldness susceptibility locus at 20p11 |
| title_sort |
male-pattern baldness susceptibility locus at 20p11 |
| publishDate |
2008 |
| url |
https://ncbi.nlm.nih.gov/pmc/articles/PMC2672151/ https://ncbi.nlm.nih.gov/pubmed/18849991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.255 |
| _version_ |
1760750873558908928 |