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Identification of ten loci associated with height highlights new biological pathways in human growth

Height is a classic polygenic trait, reflecting the combined influence of multiple as-yet-undiscovered genetic factors. We carried out a meta-analysis of genome-wide association study data of height from 15,821 individuals at 2.2 million SNPs, and followed up the strongest findings in >10,000 sub...

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Autors principals: Lettre, Guillaume, Jackson, Anne U, Gieger, Christian, Schumacher, Fredrick R, Berndt, Sonja I, Sanna, Serena, Eyheramendy, Susana, Voight, Benjamin F, Butler, Johannah L, Guiducci, Candace, Illig, Thomas, Hackett, Rachel, Heid, Iris M, Jacobs, Kevin B, Lyssenko, Valeriya, Uda, Manuela, Boehnke, Michael, Chanock, Stephen J, Groop, Leif C, Hu, Frank B, Isomaa, Bo, Kraft, Peter, Peltonen, Leena, Salomaa, Veikko, Schlessinger, David, Hunter, David J, Hayes, Richard B, Abecasis, Gonçalo R, Wichmann, H-Erich, Mohlke, Karen L, Hirschhorn, Joel N
Format: Article
Idioma:English
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687076/
https://ncbi.nlm.nih.gov/pubmed/18391950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.125
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