CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling

CD95 is a multifunctional receptor that induces cell death or proliferation depending on the signal, cell type, and cellular context. Here, we describe a thus far unknown function of CD95 as a silencer of T cell activation. Naive human T cells triggered by antigen-presenting cells expressing a membr...

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Main Authors: Strauss, Gudrun, Lindquist, Jonathan A., Arhel, Nathalie, Felder, Edward, Karl, Sabine, Haas, Tobias L., Fulda, Simone, Walczak, Henning, Kirchhoff, Frank, Debatin, Klaus-Michael
Format: Artigo
Jezik:English
Izdano: The Rockefeller University Press 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715064/
https://ncbi.nlm.nih.gov/pubmed/19487421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082363
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2715064/
https://ncbi.nlm.nih.gov/pubmed/19487421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082363

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