In vitro Hematopoietic Differentiation of Mouse Embryonic Stem Cells Requires the Tumor Suppressor Menin and is Mediated by Hoxa9

Inactivating mutations in the tumor suppressor gene MEN1 cause the inherited cancer syndrome multiple endocrine neoplasia type 1 (MEN1). The ubiquitously expressed MEN1 encoded protein, menin, interacts with MLL (mixed-lineage leukemia protein), and together they are essential components of a multip...

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Autors principals: Novotny, Elizabeth, Compton, Sheila, Liu, P. Paul, Collins, Francis S., Chandrasekharappa, Settara C.
Format: Article
Idioma:English
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717021/
https://ncbi.nlm.nih.gov/pubmed/19393316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2009.04.001
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2717021/
https://ncbi.nlm.nih.gov/pubmed/19393316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2009.04.001

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