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Effector-memory T cell responses are associated with protection of rhesus monkeys from mucosal SIV challenge

The rapid onset of massive, systemic viral replication during primary HIV/SIV infection and the immune evasion capabilities of these viruses pose fundamental problems for vaccines that depend upon initial viral replication to stimulate effector T cell expansion and differentiation1–5. We hypothesize...

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Bibliografische gegevens
Hoofdauteurs: Hansen, Scott G., Vieville, Cassandra, Whizin, Nathan, Coyne-Johnson, Lia, Siess, Don C., Drummond, Derek D., Legasse, Alfred W., Axthelm, Michael K., Oswald, Kelli, Trubey, Charles M., Piatak, Michael, Lifson, Jeffrey D., Nelson, Jay A., Jarvis, Michael A., Picker, Louis J.
Formaat: Artikel
Taal:English
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720091/
https://ncbi.nlm.nih.gov/pubmed/19219024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1935
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