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The Development of Resistance to Passive Therapy by a Potently Neutralizing Humanized West Nile Virus Monoclonal Antibody

Previous studies have established the therapeutic efficacy of humanized E16 (hE16) monoclonal antibody against West Nile virus (WNV) in animals. Here, we assess the potential for WNV strains encoding mutations in the hE16 epitope to resist passive immunotherapy and for the selection of neutralizatio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Shuliu, Vogt, Matthew R., Oliphant, Theodore, Engle, Michael, Bovshik, Evgeniy I., Diamond, Michael S., Beasley, David W. C.
Formatua: Artikulua
Hizkuntza:English
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752978/
https://ncbi.nlm.nih.gov/pubmed/19527169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/599794
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